Thermo Fisher Scientific Angiotensin I Converting Enzyme (ACE)/CD143 Monoclonal Antibody (9B9)
인간 ACE/CD143 단백질을 표적으로 하는 Mouse Monoclonal Antibody(클론 9B9). IHC(P), IHC(PFA), ELISA 등에 사용 가능하며, 단백질 A/G 정제, PBS 용액 형태로 제공. 혈압 조절 관련 효소 연구용에 적합.
- 카탈로그번호
- 1636-MSM1-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9B9 |
| Immunogen | Full-length recombinant human ACE/CD143 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes an enzyme that catalyzes the conversion of angiotensin I into the physiologically active peptide angiotensin II.
Angiotensin II acts as a potent vasopressor and aldosterone-stimulating peptide, regulating blood pressure and fluid-electrolyte balance.
ACE plays a key role in the renin-angiotensin system.
Studies have linked a 287 bp Alu repeat element in this gene with circulating enzyme levels and cardiovascular pathophysiologies.
Two major alternatively spliced variants encode somatic and testicular isozymes, both equally active.
Additional alternatively spliced variants have been identified, though their full-length sequences remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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