Thermo Fisher Scientific Phospho-ZAP70 (Tyr319) Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
A302007A | - | Thermo Fisher Scientific A302007A Phospho-ZAP70 (Tyr319) Polyclonal Antibody 100 ul pk | 재고문의 | pk | 704,000원 | - | 774,400원 | |
A302007AT | - | Thermo Fisher Scientific A302007AT Phospho-ZAP70 (Tyr319) Polyclonal Antibody 10 ul pk | 재고문의 | pk | 195,000원 | - | 214,500원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
Flow Cytometry (Flow)
1.0 µg/1x10^6 cells in 150 µL
Immunoprecipitation (IP)
2-5 µg/mg lysate
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region including tyrosine 319 (when it is phosphorylated) of Human zeta-chain (TCR) associated protein kinase 70kDa. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Zap-70,
uniProtId:
P43403-1,
ncbiNodeId:
9606,
antigenRange:
319,
antigenLength:
619,
antigenImageFileName:
A302-007A_Zap-70_P43403-1_Rabbit.svg,
antigenImageFileNamePDP:
A302-007A_Zap-70_P43403-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
ZAP-70 is a cytosolic protein tyrosine kinase that is a member of the Syk family of proteins. ZAP-70 is expressed exclusively in T-cells and natural killer cells and is required for T-cell receptor activation. Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains. Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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