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Thermo Fisher Scientific Beta-catenin Polyclonal Antibody
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Thermo Fisher Scientific Beta-catenin Polyclonal Antibody

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Beta-catenin 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal 항체로, Western Blot, IHC, IP, ChIP-Seq 등 다양한 응용에 적합합니다. 인간 유래 항원(760-781 aa)을 기반으로 제작되었으며, 4°C 보관 및 Wet ice 배송 조건을 권장합니다.

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마지막 업데이트 2025. 08. 05. 오후 08:17
Thermo Fisher Scientific A302012AM Beta-catenin Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
477,300원VAT 포함 525,030원
Thermo Fisher Scientific A302012AT Beta-catenin Polyclonal Antibody 10 ul pk판매 단위 pk ·
재고 확인 필요
194,600원VAT 포함 214,060원

Thermo Fisher Scientific · Thermo Fisher Scientific Beta-catenin Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution / Amount
Western Blot (WB) 1:2,000–1:10,000
Immunohistochemistry (IHC) 1:100–1:500
Immunohistochemistry (Paraffin) (IHC (P)) 1:100–1:500
Immunoprecipitation (IP) 2–5 µg/mg lysate
ChIP-sequencing (ChIP-Seq) 4 µg/30 µg chromatin

Product Specifications

Specification Detail
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Region between residue 760 and 781 of human beta-catenin
Conjugate Unconjugated
Form Liquid
Concentration 0.20 mg/mL
Storage Conditions 4°C
Shipping Conditions Wet ice

Product Specific Information

  • Recommended shelf life: 1 year from date of receipt
  • For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
  • Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, Bovine, and Dog.

Target Information

Beta-catenin is an adherens junction (AJ) protein involved in cell-cell adhesion and signaling.

  • Functions in the formation and maintenance of epithelial layers by linking E-cadherin to the actin cytoskeleton via alpha-catenin.
  • Interacts with cytoskeletal complexes and signaling pathways including tyrosine kinases, phosphatases, and Wnt/Wingless.
  • Expressed in hair follicle cells, basal and peripheral matrix cells, and outer/inner root sheath cells.
  • Implicated in various cancers such as pilomatrixoma, medulloblastoma, colorectal, ovarian, and other solid tumors.
  • In the nucleus, beta-catenin co-activates Lef/Tcf transcription factors, stimulating genes like cyclin D and c-myc, promoting cell proliferation and tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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