Thermo Fisher Scientific VPS51 Polyclonal Antibody
VPS51 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, -20°C에서 저장 권장. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human VPS51 (NP_0373972) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.55 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806137 |
Product Specific Information
Immunogen sequence:
MAAAAAAGPS PGSGPGDSPE GPEGEAPERR RKAHGMLKLY YGLSEGEAAG RPAGPDPLDP TDLNGAHFDP EVYLDKLRRE CPLAQLMDSE TDMVRQIRAL DSDMQTLVYE NYNKFISATD TIRKMKNDFR KMEDEMDRLA TNMAVITDFS ARISATLQDR HERITKLAGV HALLRKLQFL FELPSRLTKC VELGAYGQAV RYQGRAQAVL QQYQHLPSFR AIQDDCQVIT ARLAQQLRQR FREGGSGAPE QAECVELLLA
Positive Samples: A-549
Cellular Location: Golgi apparatus, Recycling endosome, trans-Golgi network
Target Information
VPS51 acts as a component of the GARP complex involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). It is required for protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic, and autophagy. VPS51 also functions as part of the EARP complex associated with Rab4-positive endosomes, promoting recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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