Thermo Fisher Scientific CHRNA4 Polyclonal Antibody, MaxPab
CHRNA4 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, PBS 완충액에 보관됩니다. 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHRNA4 (AAH96292.1, 1 a.a.–approximately 451 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKFGSWTYDK AKIDLVNMHS RVDQLDFWES GEWVIVDAVG TYNTRKYECC AEIYPDITYA FVIRRLPLFY TINLIIPCLL ISCLTVLVFY LPSECGEKIT LCISVLLSLT VFLLLITEII PSTSLVIPLI GEYLLFTMIF VTLSIVITVF VLNVHHRSPR THTMPTWVRR VFLDIVPRLL LMKRPSVVKD NCRRLIESMH KMASAPRFWP EPEGEPPATS GTQSLHPPSP SFCVPLDVPA EPGPSCKSPS DQLPPQQPLE AEKASPHPSP GPCRPPHGTQ APGLAKARSL SVQHMSSPGE AVEGGVRCRS RSIQYCVPRD DAAPEADGQA AGALASRNTH SAELPPPDQP SPCKCTCKKE PSSVSPSATV KTRSTKAPPP HLPLSPALTR AVEGVQYIAD HLKAEDTDFS VKEDWKYVAM VIDRIFLWMF IIVCLLGTVG LFLPPWLAGM I
Target Information
This gene encodes a nicotinic acetylcholine receptor, part of the ligand-gated ion channel superfamily responsible for fast synaptic signal transmission. These pentameric receptors bind acetylcholine, inducing conformational changes that open an ion-conducting channel across the plasma membrane. The CHRNA4 protein forms functional receptors with nAChR beta-2 or beta-4 subunits. Mutations in this gene are associated with nocturnal frontal lobe epilepsy type 1, and certain polymorphisms may confer protection against nicotine addiction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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