Thermo Fisher Scientific CHRNA4 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MKFGSWTYDK AKIDLVNMHS RVDQLDFWES GEWVIVDAVG TYNTRKYECC AEIYPDITYA FVIRRLPLFY TINLIIPCLL ISCLTVLVFY LPSECGEKIT LCISVLLSLT VFLLLITEII PSTSLVIPLI GEYLLFTMIF VTLSIVITVF VLNVHHRSPR THTMPTWVRR VFLDIVPRLL LMKRPSVVKD NCRRLIESMH KMASAPRFWP EPEGEPPATS GTQSLHPPSP SFCVPLDVPA EPGPSCKSPS DQLPPQQPLE AEKASPHPSP GPCRPPHGTQ APGLAKARSL SVQHMSSPGE AVEGGVRCRS RSIQYCVPRD DAAPEADGQA AGALASRNTH SAELPPPDQP SPCKCTCKKE PSSVSPSATV KTRSTKAPPP HLPLSPALTR AVEGVQYIAD HLKAEDTDFS VKEDWKYVAM VIDRIFLWMF IIVCLLGTVG LFLPPWLAGM I

Target Information

This gene encodes a nicotinic acetylcholine receptor, belonging to a superfamily of ligand-gated ion channels that mediate fast synaptic signal transmission. These pentameric receptors bind acetylcholine, causing conformational changes that open an ion channel across the plasma membrane. The CHRNA4 protein interacts with nAChR beta-2 or beta-4 subunits to form functional receptors. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1, and certain polymorphisms are associated with protection against nicotine addiction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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