Thermo Fisher Scientific CHRNB1 Monoclonal Antibody (4G4)
인체 CHRNB1 단백질을 인식하는 Mouse IgG3 단일클론 항체. Western blot 및 ELISA에 사용 가능. GST 태그 결합 재조합 단백질로 면역화. PBS(pH 7.4) 용액 형태로 제공되며 보존제 무첨가. -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4G4 |
| Immunogen | CHRNB1 (NP_000738, 24 a.a.–128 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SEAEGRLREK LFSGYDSSVR PAREVGDRVR VSVGLILAQL ISLNEKDEEM STKVYLDLEW TDYRLSWDPA EHDGIDSLRI TAESVWLPDV VLLNNNDGNF DVALD
Target Information
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit.
This gene encodes the beta subunit of the acetylcholine receptor. The receptor changes conformation upon acetylcholine binding, leading to the opening of an ion-conducting channel across the plasma membrane.
Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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