Thermo Fisher Scientific CHRNB1 Monoclonal Antibody (4G4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

4G4

Immunogen

CHRNB1 (NP_000738, 24 a.a. approximately 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHRNB1,uniProtId:P11230-1,ncbiNodeId:9606,antigenRange:24-128,antigenLength:501,antigenImageFileName:H00001140-M01_CHRNB1_P11230-1_House_mouse.svg,antigenImageFileNamePDP:H00001140-M01_CHRNB1_P11230-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SEAEGRLREK LFSGYDSSVR PAREVGDRVR VSVGLILAQL ISLNEKDEEM STKVYLDLEW TDYRLSWDPA EHDGIDSLRI TAESVWLPDV VLLNNNDGNF DVALD

Target Information

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.