Thermo Fisher Scientific Carboxypeptidase B2 Monoclonal Antibody (5081)
Human TAFI를 인식하는 mouse monoclonal antibody로 Western blot과 ELISA에 최적화됨. Unconjugated 형태로 10 mg/mL 농도의 액상 제품. SDS-PAGE로 정제되었으며 -20°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Carboxypeptidase B2 Monoclonal Antibody (Clone 5081)
Applications and Tested Dilution
- Western Blot (WB): 5 µg/mL
- ELISA: 5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5081 |
| Immunogen | Human TAFI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 10.0 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087664 |
Product Specific Information
MA1-43026 detects TAFI in human samples.
It has been successfully used in Western blot and ELISA applications.
MA1-43026 was derived from human TAFI.
Target Information
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases.
Based on substrate specificity, these enzymes are classified as:
- Carboxypeptidase A: Cleaves aliphatic residues
- Carboxypeptidase B: Cleaves basic amino residues
CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and promoter region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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