Thermo Fisher Scientific Factor XI Monoclonal Antibody (5061)
인간 Factor XI를 인식하는 Thermo Fisher의 단클론 항체로, Western blot, ELISA, RIA 등 다양한 분석에 사용 가능. 비결합형 액상 형태이며, 높은 순도(SDS-PAGE 정제)와 안정성을 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 5–10 µg/mL | |
| ELISA (ELISA) | 5–10 µg/mL | |
| Radioimmune Assays (RIA) | 5–10 µg/mL | |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5061 |
| Immunogen | Human factor XI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 10.8 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074349 |
Product Specific Information
MA1-43021 detects Factor XI in human samples.
It has been successfully used in Western blot (non-reducing) and radioimmunoassay applications.
MA1-43021 was derived from human factor XI.
Target Information
This gene encodes coagulation factor XI, a key component of the blood coagulation cascade.
Factor XI exists in plasma as a zymogen and is unique among plasma coagulation enzymes because it forms a homodimer of two identical polypeptide chains linked by disulfide bonds.
Upon activation by factor XIIa, internal peptide bonds are cleaved, producing activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds.
Activated factor XIa triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Defects in this factor can lead to Rosenthal syndrome, a blood coagulation abnormality.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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