Thermo Fisher Scientific Carboxypeptidase B2 Monoclonal Antibody (5024)
Human TAFI를 인식하는 마우스 단클론 항체로 Western blot, ELISA, Inhibition Assay에 사용 가능. 비결합형 액상 포맷이며 10 mg/mL 농도. -20°C에서 보관, 동결·해동 반복 피해야 함. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 5 µg/mL | |
| ELISA (ELISA) | 5–10 µg/mL | |
| Inhibition Assays (IA) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5024 |
| Immunogen | Human TAFI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 10 mg/mL |
| Purification | SDS-PAGE |
| Storage Buffer | 50% water with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1087665 |
Product Specific Information
MA1-43023 detects TAFI in human samples.
It has been validated for use in Western Blot, ELISA, and Inhibition Assay applications.
This antibody was derived from human TAFI and activated TAFI.
Target Information
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine-, and cysteine-type enzymes. According to substrate specificity, they are classified as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues).
CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and promoter region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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