Thermo Fisher Scientific Carboxypeptidase B2 Monoclonal Antibody (5024)

Applications

Tested Dilution

Publications

Western Blot (WB)

5 µg/mL

-

ELISA (ELISA)

5-10 µg/mL

-

Inhibition Assays (IA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

5024

Immunogen

Human TAFI

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

10 mg/mL

Purification

SDS-PAGE

Storage buffer

50% water with 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1087665

Product Specific Information

MA1-43023 detects TAFI in human samples.

MA1-43023 has successfully been used in Western Blot, ELISA, and Inhibition Assay applications.

MA1-43023 was derived from human TAFI and activated TAFI.

Target Information

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.