Thermo Fisher Scientific Interferon alpha/beta receptor 1 Recombinant Rabbit Monoclonal Antibody (BLR265L)
Human IFNAR1 단백질을 인식하는 Rabbit Recombinant Monoclonal 항체로, Western blot, IHC, IP에 사용 가능. 고순도 정제된 액상 형태이며 1 mg/mL 농도. 4°C 보관, 연구용 전용.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR265L |
| Immunogen | Recombinant protein representing the extracellular domain of Human Interferon alpha/beta receptor 1 (residues 27–436) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferons are widely used therapeutic agents because of their anti-tumor and antiviral effects, and because of their modulatory effects on the immune system (Biron, 2001; Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon Receptor (IFNAR1). Downregulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This downregulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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