Thermo Fisher Scientific DEFA1 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 DEFA1 폴리클로날 항체로, Rabbit IgG 기반. IHC(P)에서 사용 가능하며, 합성 펩타이드(aa 30-70)를 면역원으로 제작. 항원 친화 크로마토그래피로 정제된 고순도 항체로 연구용에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 30–70 of Human Defensin alpha1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719164 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. Purity >95% (by SDS-PAGE).
Target Information
Defensins are a family of microbicidal and cytotoxic peptides involved in host defense. They are abundant in neutrophil granules and epithelial surfaces of mucosal tissues such as intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family share high sequence similarity and a conserved cysteine motif.
Defensin alpha 1 is located in neutrophil granules and contributes to phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. DEFA1 differs from DEFA3 by only one amino acid, and both genes exhibit copy number variation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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