Thermo Fisher Scientific Livin Polyclonal Antibody
Livin 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 적합합니다. 인간 및 생쥐 반응성을 가지며 항원 친화 크로마토그래피로 정제되었습니다. 세포 사멸 관련 연구에 활용 가능하며 고순도(>95%) 제품입니다.
- 카탈로그번호
- PA575440
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- pk
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Thermo Fisher Scientific Livin Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: [References available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 180–230 of Human Livin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719168 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs possess at least one baculovirus IAP repeat (BIR) motif essential for their anti-apoptotic activity.
Livin (also known as ML-IAP) is a novel human IAP family member containing a single BIR domain and a COOH-terminal RING finger domain. The Livin gene has two splicing variants (298 and 280 amino acids) that both include BIR and RING domains. Both isoforms inhibit TNFα-induced apoptosis in Jurkat cells. Livin expression is low in adult tissues but higher in developmental tissues and many cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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