
ELK Biotechnology Cytokeratin 19 rabbit pAb
Cytokeratin 19 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간 유래 합성 펩타이드로 면역화되었으며, 세포골격 및 상피 세포 구조 연구에 적합. -20°C에서 1년 보관 가능.
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Cytokeratin 19 rabbit pAb
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| 항목 | 내용 |
|---|---|
| Product name | Cytokeratin 19 rabbit pAb |
| Alternative Names | KRT19; Keratin; type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Keratin 19 (AA range: 231–280) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kD |
| Gene ID (Human) | 3880 |
| Human Swiss-Prot No. | P08727 |
| Cellular Localization | Intermediate filament, plasma membrane, dystrophin-associated glycoprotein complex, Z disc, sarcolemma, costamere, extracellular exosome, cell periphery, terminal web |
| Species Reactivity | Human, Mouse, Rat |
Background
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for maintaining the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Type I cytokeratins consist of acidic proteins arranged in heterotypic pairs. Unlike related family members, Cytokeratin 19 is the smallest known acidic cytokeratin and is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, a transient superficial layer enveloping the developing epidermis. The type I cytokeratins are clustered in the chromosome region 17q12–q21. (RefSeq, Jul 2008)
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