ELK Biotechnology Cytokeratin 13 rabbit pAb
Cytokeratin 13 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 세포 골격 및 상피 구조 연구에 활용됩니다. -20°C에서 1년 보관 가능합니다.
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Cytokeratin 13 rabbit pAb
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| 항목 | 내용 |
|---|---|
| Product name | Cytokeratin 13 rabbit pAb |
| Alternative Names | KRT13; Keratin; type I cytoskeletal 13; Cytokeratin-13; CK-13; Keratin-13; K13 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cytokeratin 13 (AA range: 233–282) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 52 kD |
| GeneID (Human) | 3860 |
| Human Swiss-Prot No | P13646 |
| Cellular Localization | nucleus; intermediate filament; keratin filament; intermediate filament cytoskeleton; extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the keratin gene family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most type I cytokeratins are acidic proteins arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 are associated with the autosomal dominant disorder White Sponge Nevus. Type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants, though not all have been described. (RefSeq, Jul 2008)
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