ELK Biotechnology Cystatin C rabbit pAb
Cystatin C 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 사용 가능. 고순도 IgG 형태로 제공되며, 다양한 종(Human, Mouse, Rat, Monkey)에 반응. -20°C에서 장기 보관 가능.
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Cystatin C rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cystatin C rabbit pAb |
| Alternative Names | CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from Cystatin C (AA range: 60-140) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 15 kD |
| GeneID (Human) | 1471 |
| Human Swiss-Prot No | P01034 |
| Cellular Localization | Secreted |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some members are active cysteine protease inhibitors, while others have lost or never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including type 1 cystatins (stefins), type 2 cystatins, and kininogens. Type 2 cystatin proteins are cysteine proteinase inhibitors found in various human fluids and secretions, providing protective functions. The cystatin locus on chromosome 20 contains most type 2 cystatin genes and pseudogenes. This gene encodes the most abundant extracellular inhibitor of cysteine proteases, highly expressed in biological fluids and virtually all organs. A mutation in this gene has been associated with certain pathologies.
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