
ELK Biotechnology Cyclin A rabbit pAb
Cyclin A 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 Cyclin A 유래 펩타이드로 면역 생성되었으며, 세포주기 조절 연구에 활용됩니다. 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
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Cyclin A rabbit pAb
제품 개요
Cyclin A 단백질을 인식하는 토끼 폴리클로날 항체입니다. 세포주기 조절 및 CDK 관련 연구에 유용하며, 다양한 응용 분야(WB, IHC, IF, ELISA)에 사용할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cyclin A rabbit pAb |
| Alternative Names | CCNA1; Cyclin-A1; CCNA2; CCN1; CCNA; Cyclin-A2; Cyclin-A |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Cyclin A (AA range: 221–270) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 53 kDa |
| Gene ID (Human) | 8900 / 890 |
| Human Swiss-Prot No | P78396 / P20248 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat; Monkey |
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, characterized by periodic expression during the cell cycle. Cyclins regulate CDK kinases and exhibit distinct expression and degradation patterns that coordinate mitotic events. Cyclin A is expressed in testis, brain, and leukemic cell lines, functioning mainly in the control of germline meiotic cell cycle. It binds to CDK2 and CDC2 kinases, providing distinct kinase activities in S and G2 phases. Additionally, Cyclin A interacts with key cell cycle regulators such as Rb family proteins, transcription factor E2F-1, and p21 family proteins.
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