ELK Biotechnology Caspase-2 rabbit pAb
Caspase-2 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 세포사멸 및 신경퇴행성 질환 연구에 활용 가능하며, 고순도의 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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Caspase-2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Caspase-2 rabbit pAb |
| Alternative Names | CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human Caspase-2 (AA range: 123–172) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 51 kDa |
| Gene ID (Human) | 835 |
| Human Swiss-Prot No. | P42575 |
| Cellular Localization | Nucleus, cytoplasm, mitochondrion, cytosol, membrane |
| Species Reactivity | Human, Rat, Mouse |
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer’s disease, Huntington’s disease, and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Jan 2011)
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