ELK Biotechnology Bmx rabbit pAb
Bmx rabbit pAb는 인간 및 마우스 시료에서 Bmx 단백질을 검출하기 위한 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 적합하며, 고순도의 IgG로 제작되었습니다. 세포 신호전달 및 암 연구에 유용합니다. -20°C에서 1년간 보관 가능합니다.
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ELK Biotechnology Bmx rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Bmx rabbit pAb |
| Alternative Names | BMX; Cytoplasmic tyrosine-protein kinase BMX; Bone marrow tyrosine kinase gene in chromosome X protein; Epithelial and endothelial tyrosine kinase; ETK; NTK38 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 Immunohistochemistry: 1/100–1/300 Immunofluorescence: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human C-terminal ETK (AA range: 532–581) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 78 kD |
| Gene ID (Human) | 660 |
| Human Swiss-Prot No. | P51813 |
| Cellular Localization | Cytoplasm. Localizes to the edges of spreading cells when complexed with BCAR1. |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene.
[Provided by RefSeq, Mar 2016]
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