ELK Biotechnology COX6c rabbit pAb
COX6c 단백질을 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인체 COX6C 유래 합성 펩타이드로 면역화됨. 미토콘드리아 내막 단백질 검출에 적합하며, 사람, 마우스, 랫트에 반응. -20°C에서 1년 보관.
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COX6c rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | COX6c rabbit pAb |
| Alternative Names | COX6C; Cytochrome c oxidase subunit 6C; Cytochrome c oxidase polypeptide VIc |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 Immunofluorescence: 1/200 - 1/1000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human COX6C (AA range: 11-60) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 32 kD |
| GeneID (Human) | 1345 |
| Human Swiss-Prot No | P09669 |
| Cellular Localization | Mitochondrion inner membrane; Single-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosome 16p12. (Provided by RefSeq, Jul 2010)
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