ELK Biotechnology c-Maf rabbit pAb
c-Maf 단백질을 인식하는 토끼 폴리클로날 항체로, WB와 ELISA에 적합합니다. 인간 Maf 유래 펩타이드로 제작되었으며 핵 내 단백질 검출에 사용됩니다. 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology c-Maf rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | c-Maf rabbit pAb |
| Alternative Names | MAF; Transcription factor Maf; Proto-oncogene c-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Maf (AA range: 301-350) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 41 kD |
| GeneID (Human) | 4094 |
| Human Swiss-Prot No | O75444 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
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