Thermo Fisher Scientific Cdc2 p34 Monoclonal Antibody (POH-1)
Cdc2 p34 단백질을 특이적으로 인식하는 단클론 항체로, 인체 및 설치류 시료에서 높은 반응성을 보입니다. Western blot, ELISA, IP 등에 적합하며 Protein A로 정제된 액상 형태입니다. -20°C에서 안정적으로 보관 가능하며 연구용으로만 사용됩니다.
- 카탈로그번호
- 200-301-160
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- pk
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Thermo Fisher Scientific Cdc2 p34 Monoclonal Antibody (POH-1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:5,000–1:20,000 |
| Immunoprecipitation (IP) | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | POH-1 |
| Immunogen | This protein A purified monoclonal antibody was produced by repeated immunizations with recombinant human p34 cdc2 fusion protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.5M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
Reacts specifically with p34 cdc2 in human tissues and cell lines. This antibody is not cross-reactive with other cyclin dependent kinases. Cross-reactivity with p34 cdc2 from other sources, especially mouse and rat, will occur. This reagent has broad interspecies reactivity.
Target Information
CDK1 (Cell Division Control protein 1) is essential for the completion of START, the controlling event in the cell cycle required to initiate mitosis. CDK1 is a catalytic subunit of the M-Phase Promoting Factor, which induces entry into mitosis and is universal among eukaryotes. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays apoptosis onset. The therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer has also been demonstrated.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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