Thermo Fisher Scientific SOD3 Monoclonal Antibody (4GG11G6)
SOD3 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat, Guinea pig 반응성. Protein G 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보관. -20°C에서 저장.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | 1:100 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| ELISA | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4GG11G6 |
| Immunogen | Human extracellular SOD purified from aortas |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735368 |
Additional Formats
Product Specific Information
- 1 µg/mL of MA5-27661 was sufficient for detection of EC-SOD in 20 µg of human cartilage lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects extracellular SOD approximately 35 kDa.
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and has increased expression in actively dividing cells such as testis, thymus, fetal liver, and carcinomas. The protein localizes to the nucleus and promotes the stability and nuclear accumulation of transcriptionally active p53. It phosphorylates Thr18 of p53, reducing ubiquitination and potentially regulating cell proliferation. Additionally, it phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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