Thermo Fisher Scientific CD61 Monoclonal Antibody (256809), PE
PE 형광 표지된 CD61 단일클론 항체로 인간 세포에서 Integrin β3 검출에 사용. Flow Cytometry에 적합하며, 교차반응 없음. 단백질 A/G 정제, 4°C 암소 보관, 연구용 전용.
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Thermo Fisher Scientific CD61 Monoclonal Antibody (256809), PE
Applications
- Flow Cytometry (Flow): 10 µL per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 256809 |
| Immunogen | CHO-derived recombinant human Integrin beta 3/CD61 (Gly27–Asp718) |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | Buffered saline solution with BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609719 |
Additional Formats
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Integrin beta 1, beta 2, recombinant mouse Integrin beta 4, or beta 6 is observed.
Target Information
CD61 (GPIIIa, ITGB3) is a glycoprotein found on megakaryocytes, platelets, and their precursors.
It plays a role in platelet aggregation and acts as a receptor for fibrinogen, fibronectin, von Willebrand factor, and vitronectin.
CD61 (105 kDa) associates with either αIIb integrin (CD41) or αV integrin (CD51) at the cell surface.
It is expressed on platelets, megakaryocytes, endothelial cells, monocytes, and osteoclasts.
CD61 participates in cell adhesion and signaling; dysfunctions are linked to Glanzmann Thrombasthenia and Platelet type-16 Bleeding Disorder.
Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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