Thermo Fisher Scientific JAB1 Monoclonal Antibody (2A10)
JAB1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 2A10). Western blot, IHC, ICC, IP 등 다양한 응용에 적합. 1 mg/mL 농도의 액상 형태로 제공되며, Protein G로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | 1 publication |
| Immunoprecipitation (IP) | 0.5–1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A10 |
| Immunogen | Full-length mouse JAB-1 gene expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term); at -20°C (long term, avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_559734 |
Product Specific Information
Recommended positive controls: 293T, A431, HeLa, HepG2, MCF-7, MDA-MB-231, Rat liver.
Target Information
JAB-1 is a 38 kDa protein originally described as a coactivator for cJUN. It is part of the large protein complex known as the Signalosome, which plays a signaling role in mammalian cells and is analogous to the COP9 complex in plants. JAB-1 may be involved in targeting proteins for degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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