Thermo Fisher Scientific JAB1 Monoclonal Antibody (6C3.38)
JAB1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, IHC, ICC, IP 등에 사용 가능. Human, Mouse, Rat 시료에 반응하며, Protein G로 정제된 액상 형태. 1 mg/mL 농도로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Immunoprecipitation (IP) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C3.38 |
| Immunogen | The full-length mouse JAB-1 gene expressed in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_559735 |
Product Specific Information
Recommended positive controls: 293 cell lysate.
Target Information
JAB-1 is a 38 kDa protein originally described as a coactivator for cJUN. It is part of a large protein complex called the Signalosome, which is proposed to play a signaling role in mammalian cells. This complex is analogous to the COP9 complex in plants, important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has been implicated in targeting proteins for degradation by the proteasome.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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