Thermo Fisher Scientific NUP153 Polyclonal Antibody
NUP153 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 면역세포화학(ICC/IF)에 적합합니다. 사람, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NUP153 (Accession P49790), corresponding to amino acid residues G1301–F1351. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900312 |
Product Specific Information
This antibody detects endogenous levels of total Nup153.
Target Information
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm.
The protein encoded by this gene has three distinct domains:
- N-terminal region containing a pore targeting and RNA-binding domain
- Central region containing multiple zinc finger motifs
- C-terminal region containing multiple XFXFG repeats
Alternative splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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