Thermo Fisher Scientific RRAS2 Polyclonal Antibody
RRAS2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, Jurkat cell lysate를 양성 대조로 권장. 인간 및 마우스 반응성, 액상 형태, 항원 친화 크로마토그래피로 정제됨.
- 카탈로그번호
- PA534518
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human RRAS2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551870 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-34518 can be used with blocking peptide PEP-1561.
Target Information
RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS, and H-RAS) have been widely investigated as key events in the development of human cancers.
The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21), and RRAS3 (M-Ras), showing overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras, and N-Ras) of 55–60%.
RRAS2 is a small GTP-binding protein of the Ras superfamily of GTPases. It may transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins.
RRAS2 has high oncogenic potential, and overexpression or mutations have been reported in several tumor tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-34518_RRAS2_P62070-1_Rabbit.svg)
(이미지: PA5-34518_RRAS2_P62070-1_Rabbit_PDP.jpeg)
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