Thermo Fisher Scientific BAG3 Polyclonal Antibody
인간 BAG3 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot과 IHC(Paraffin) 실험에 적합하며, 고순도 암모늄 황산 침전으로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-KNAGNAEDPHTE (aa 537–548) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2932952 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
BAG3 belongs to the BAG protein family, which competes with Hip for binding to the Hsc70/Hsp70 ATPase domain and promotes substrate release. All BAG proteins contain an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The BAG3 protein includes a WW domain in the N-terminal region and a BAG domain in the C-terminal region. BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain both in vitro and in mammalian cells, binding with high affinity and inhibiting its chaperone activity in a Hip-repressible manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-142301_BAG3_O95817-1_Goat.svg
- PA5-142301_BAG3_O95817-1_Goat_PDP.jpeg
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