Thermo Fisher Scientific ZNF638 Polyclonal Antibody
ZNF638 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며, 인간·마우스·랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로, DNA 결합 및 전사 조절 연구에 활용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF638 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1308–1353 of human ZNF638 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553858 |
Product Specific Information
This antibody detects endogenous ZNF638 protein at molecular weights of 220 kDa and 120 kDa (Isoform 5).
Purity is >95% by SDS-PAGE.
Target Information
Zinc-finger proteins contain DNA-binding domains and are involved in transcriptional activation or repression.
NP220 (ZNF638), also known as Cutaneous T-cell lymphoma-associated antigen se33-1, is a 1978 amino acid protein with one matrin-type zinc finger and two RNA recognition motif (RRM) domains, indicating a role in transcriptional regulation.
NP220 binds to double-stranded DNA fragments by recognizing clusters of cytidines, interacts with FHL-2, and is phosphorylated by ATM or ATR upon DNA damage.
It exists in five isoforms due to alternative splicing; Isoform 5 is a tumor-associated antigen found in several cutaneous T-cell lymphomas (CTCL), including mycosis fungoides and Sezary syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 정보 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.