Thermo Fisher Scientific NRL Polyclonal Antibody
Thermo Fisher Scientific의 NRL Polyclonal Antibody는 인간, 생쥐, 랫트 시료에서 NRL 단백질을 검출하기 위한 rabbit polyclonal 항체입니다. Western blot에 적합하며, 고순도(>95%)로 정제되었습니다. 장기 보관 시 -20°C에서 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 42–87 of human NRL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553859 |
Product Specific Information
This antibody detects endogenous NRL protein at a molecular weight of approximately 30 kDa.
Purity is greater than 95% by SDS-PAGE.
Target Information
Nrl (neural retina leucine zipper) is a member of the Maf family of transcription factors, characterized by a basic leucine zipper (bZIP)-DNA binding motif. Both Nrl and c-Maf preferentially bind to T-MARE sites and play roles in developmental and physiological processes. The Maf-Nrl subfamily regulates expression of cell type-specific genes in hematopoietic tissues, cerebellum, and developing hindbrain. Nrl promotes rhodopsin expression in retinal cells by binding to the Nrl response element in the rhodopsin promoter. It is expressed during neuronal differentiation and later restricted to neocortex, brainstem, and retinal neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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