Thermo Fisher Scientific SMAD6 Polyclonal Antibody
SMAD6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 적합합니다. 인간, 마우스, 원숭이, 양, 랫드에 반응하며, 내부 합성 펩타이드(aa 30-150)를 면역원으로 제작되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–2 µg/mL | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–10 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 1–5 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Sheep, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal portion of human SMAD6 (between amino acids 30–150) [UniProt O43541] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2302345 |
Product Specific Information
- Predicted to react with equine based on sequence homology.
- Suggested positive control: HeLa or NIH-3T3 whole cell lysate.
Target Information
SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta type 1 receptor superfamily members. It selectively inhibits BMP (bone morphogenetic protein) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is classified as an inhibitory SMAD (I-SMAD) or antagonistic SMAD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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