Thermo Fisher Scientific TRF2 Polyclonal Antibody
인간 TRF2 단백질을 인식하는 Goat Polyclonal 항체로 다양한 응용 분야(WB, IHC, ICC, Flow, IP, ChIP)에 사용 가능. 단백질 G 정제, PBS 버퍼 및 sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific TRF2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 15 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:10–1:500 |
| Flow Cytometry (Flow) | Assay-Dependent |
| Immunoprecipitation (IP) | 2 µg/million cells |
| ChIP assay (ChIP) | 1:20–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Baculovirus-expressed His-tagged full-length TRF2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2201476 |
Product Specific Information
Suggested positive control: antigen standard for TERF2 (transient overexpression lysate), Daudi, HeLa, HL-60, or Jurkat.
Target Information
TRF2 is a ubiquitously expressed protein involved in the regulation of telomere length. It contains a Myb-related DNA binding motif and binds to duplex TTAGGG repeats localized to all human telomeres in metaphase chromosomes. TRF2 helps protect chromosome ends by maintaining telomere structure and preventing senescence in primary human cells. Inhibition of TRF2 has been shown to induce apoptosis in certain mammalian cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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