Thermo Fisher Scientific SETDB1 Monoclonal Antibody (5H6A12)
SETDB1 단백질을 검출하는 Thermo Fisher Scientific의 단클론 항체. Western blot, ICC/IF, ELISA, ChIP 등 다양한 응용 가능. 인간, 생쥐, 비인간 영장류 시료에 반응. 안정적인 액상 형태로 제공되며 4°C 또는 -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | - |
| ELISA | 1:10,000 | - |
| ChIP assay (ChIP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H6A12 |
| Immunogen | Purified recombinant fragment of human SETDB1 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10988015 |
Product Specific Information
MA5-15722 targets SETDB1 in indirect ELISA, IF, and WB applications and shows reactivity with human, mouse, and non-human primate samples.
The immunogen is a purified recombinant fragment of human SETDB1 expressed in E. coli.
MA5-15722 detects SETDB1 with a predicted molecular weight of approximately 180 kDa.
Target Information
This gene encodes a histone methyltransferase. The enzyme catalyzes the reaction of S-adenosyl-L-methionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine.
The encoded protein likely functions in transcriptional repression. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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