Thermo Fisher Scientific TNFRSF11B Monoclonal Antibody (5A11)
인간 TNFRSF11B 단백질을 특이적으로 인식하는 Mouse IgG1 단클론 항체. Western blot, IHC, ELISA에 적합하며, 60kDa 단백질 검출 가능. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 냉동 보관 권장.
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Thermo Fisher Scientific TNFRSF11B Monoclonal Antibody (5A11)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A11 |
| Immunogen | Purified recombinant fragment of human TNFRSF11B expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10989307 |
Product Specific Information
MA5-15726 targets TNFRSF11B in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human TNFRSF11B expressed in E. coli.
MA5-15726 detects TNFRSF11B, which has a predicted molecular weight of approximately 60 kDa.
Target Information
The protein encoded by this gene is a member of the TNF-receptor superfamily. It functions as an osteoblast-secreted decoy receptor that negatively regulates bone resorption.
This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development.
Studies of the mouse counterpart suggest roles in lymph-node organogenesis and vascular calcification.
Alternatively spliced transcript variants have been reported, though their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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