Thermo Fisher Scientific APC7 Polyclonal Antibody
APC7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성. 고순도 Affinity chromatography 정제, PBS/glycerol buffer로 안정적 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ANAPC7 (Accession Q9UJX3), corresponding to amino acid residues 536–550 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899495 |
Product Specific Information
Antibody detects endogenous levels of total Apc7.
Target Information
Cell cycle regulated protein ubiquitination and degradation within subcellular domains is essential for normal mitosis progression.
APC7 is a conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase controlling mitosis and G1 phase progression.
APC/C degrades anaphase inhibitors, mitotic cyclins, and spindle-associated proteins to ensure proper sequence of mitotic events.
APC7 contributes to APC/C-mediated protein ubiquitination and interaction with transcription coactivators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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