Thermo Fisher Scientific BCL6 Polyclonal Antibody
인간 BCL6 단백질을 인식하는 토끼 폴리클로날 항체. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 연구용 전용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human BCL6. Recombinant protein control fragment (Product # RP-102500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789341 |
Product Specific Information
Immunogen sequence:
NIYSPKETIP EEARSDMHYS VAEGLKPAAP SARNAPYFPC DKASKEEERP SSEDEIALHF EPPNAPLNRK GLVSPQSPQK SDCQPNSPTE SCSSKNACIL QASGSPPAKS PTDPKACNWK KYKFIVLNS
Target Information
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas.
Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin’s lymphomas, and rearrangements have been detected in 33–45% of diffuse large B cell lymphomas.
Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt’s lymphomas, and in nodular, lymphocyte predominant Hodgkin’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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