Thermo Fisher Scientific APRIL Polyclonal Antibody
Human TNFSF13 단백질을 인식하는 Rabbit Polyclonal 항체. IHC(P)에서 1:200~1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 항체로, 4°C 또는 -20°C에서 보관. B세포 및 T세포 활성화 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNFSF13. Recombinant protein control fragment (Product # RP-102132) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789334 |
Product Specific Information
Immunogen sequence:
LEAWENGERS RKRRAVLTQK QKKQHSVLHL VPINATSKDD SDVTEVMWQP
ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ
VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS CYSAGVFHLH QGDILSTarget Information
Members in the TNF superfamily regulate immune responses and induce apoptosis.
A novel member in this family, APRIL (A Proliferation-Inducing Ligand), also known as TALL2 and TRDL1a, has been identified in human and mouse.
Two receptors for APRIL, TACI and BCMA, mediate its biological effects.
APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death.
APRIL and its close relative BlyS, along with receptors BCMA and TACI, are implicated in autoimmune diseases and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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