Thermo Fisher Scientific GRAP2 Monoclonal Antibody (UW40)
GRAP2/GADS 단백질을 인식하는 mouse monoclonal antibody. Western blot, Flow cytometry, Immunoprecipitation 등에 사용 가능. Protein A로 정제된 액상 항체로 4°C 보관. T 세포 신호전달 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Flow Cytometry (Flow) | 2 - 6 µg/mL | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UW40 |
| Immunogen | GST-fusion human GRAP2/GADS protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157212 |
Product Specific Information
This antibody recognizes GRAP2/GADS, a 41 kDa cytoplasmic adaptor protein that plays a pivotal role during the early events of signal transduction in T cells.
Target Information
This gene encodes a member of the GRB2/Sem5/Drk family. It is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member GRAP, this protein contains an SH2 domain flanked by two SH3 domains. It interacts with other proteins such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2) through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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