Thermo Fisher Scientific IL6 Monoclonal Antibody (OTI2C9), TrueMAB
IL-6 단백질을 검출하기 위한 마우스 모노클로날 항체로, WB 및 IHC(P) 실험에 최적화되어 있습니다. 인간 IL-6 단백질(aa 29-212)을 면역원으로 사용하였으며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능하며, 염증 및 면역 관련 연구에 적합합니다.
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Thermo Fisher Scientific IL6 Monoclonal Antibody (OTI2C9), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 29–212 of human IL-6 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
IL-6 encodes a cytokine involved in inflammation and B cell maturation. The protein acts as an endogenous pyrogen that can induce fever in autoimmune disease or infection. It is mainly expressed at sites of acute and chronic inflammation, secreted into serum, and triggers transcriptional inflammatory responses via the interleukin 6 receptor alpha.
This gene is implicated in various inflammation-associated diseases such as diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated IL-6 levels have been observed in viral infections, including COVID-19 (SARS-CoV-2).
Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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