Thermo Fisher Scientific SMAD9 Monoclonal Antibody (PCRP-SMAD9-2F4)
Thermo Fisher Scientific의 SMAD9 단클론 항체(PCRP-SMAD9-2F4)는 인간 SMAD9 단백질을 인식하는 Mouse IgG1 형 항체로, ICC/IF, Flow Cytometry, Peptide Array 등 다양한 연구 응용에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-SMAD9-2F4 |
| Immunogen | Recombinant full-length human SMAD9 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SMADs are members of the MAD-related family of molecules. These intracellular proteins are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta (TGF-β) superfamily.
SMADs are categorized as follows:
- Receptor-regulated SMADs (R-SMADs): SMAD1, 2, 5, 8, 9
- Common-mediator SMAD (co-SMAD): SMAD4
- Inhibitory SMADs (I-SMADs): SMAD6, 7
SMAD1, 5, 8, and 9 share high sequence homology, and antibodies may recognize common epitopes. SMAD8 and SMAD9 are often used interchangeably in literature. Mutations in SMAD9 are associated with pulmonary hypertension, primary type 2 (PPH2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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