Thermo Fisher Scientific Transthyretin Polyclonal Antibody
Western blot, IHC, ICC, ELISA에 사용 가능한 Transthyretin 폴리클로날 항체. Human, Mouse, Rat 반응. Rabbit IgG 기반, 0.5 mg/mL 농도, PBS/glycerol buffer. -20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21–147 of human TTR (NP_0003621) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804646 |
Product Specific Information
Immunogen sequence:
GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE
Positive Samples: HepG2, U-251MG
Cellular Location: Cytoplasm
Target Information
Transthyretin (TTR), also known as prealbumin, is a plasma protein that functions as a transporter of thyroxine and retinol-binding protein. It is primarily produced in the liver and secreted into the plasma. TTR constitutes about 25% of cerebrospinal fluid (CSF) protein, suggesting selective transport across the blood-CSF barrier or synthesis within the CNS. It is found in neuritic plaques, neurofibrillary tangles, and microangiopathic lesions of senile cerebral amyloid. Over 40 different TTR gene mutations have been linked to amyloid deposition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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