Thermo Fisher Scientific Myeloperoxidase Monoclonal Antibody (4A4)
인간 Myeloperoxidase 단백질을 인식하는 Mouse monoclonal antibody (Clone 4A4). Western blot, IHC, ELISA 등에 사용 가능하며, Protein A로 정제된 액상 형태. 4°C 보관, 연구용 전용 시약.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (IHC) | - | View 11 publications |
| ELISA | Assay-dependent | - |
| Affinity Purification (AP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A4 |
| Immunogen | Purified, full length, native, human myeloperoxidase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.6 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560236 |
Product Specific Information
MA1-20074 detects Myeloperoxidase in human samples.
Target Information
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single-chain precursor and subsequently cleaved into light and heavy chains. The mature MPO forms a tetramer composed of two light and two heavy chains. This enzyme generates hypohalous acids crucial for the microbicidal activity of neutrophils.
Diseases associated with MPO include Myeloperoxidase Deficiency and Familial Alzheimer’s Disease type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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