Thermo Fisher Scientific AMOT Monoclonal Antibody (OTI3F9), TrueMAB
AMOT 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin) 분석에 적합합니다. Human 시료에 반응하며, 고순도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되어 높은 특이성과 재현성을 보장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F9 |
| Immunogen | Full length human recombinant protein of human AMOT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs.
AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which regulates the uptake of polarity proteins at tight junctions.
It is expressed predominantly in endothelial cells of capillaries and larger vessels of the placenta, where it may mediate the inhibitory effect of angiostatin on tube formation and endothelial cell migration toward growth factors during angiogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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