Thermo Fisher Scientific SCARB1 Monoclonal Antibody (OTI1F3), TrueMAB
SCARB1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot과 Immunocytochemistry에 최적화되어 있습니다. 고순도의 Affinity chromatography 정제 방식으로 제조되었으며, 인간 유래 단백질을 면역원으로 사용합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Full-length human recombinant protein of human SCARB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with the risk of atherosclerosis.
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. It is expressed primarily in liver and nonplacental steroidogenic tissues and mediates selective cholesterol uptake by a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol storage in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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