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Thermo Fisher Scientific Phospho-Beclin 1 (Ser90, Ser93, Ser96) Polyclonal Antibody
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Beclin 1 단백질의 Ser90/93/96 인산화 상태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 사용 가능. 자가포식 연구 및 세포 신호전달 경로 분석에 적합. PBS/glycerol buffer로 안정화되어 -20°C에서 보관.
- 카탈로그번호
- PA5105647
- 판매단위
- pk
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마지막 업데이트 2025. 08. 01. 오후 01:34
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Thermo Fisher Scientific PA5105647 Phospho-Beclin 1 (Ser90, Ser93, Ser96) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
618,800원VAT 포함 680,680원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-Beclin 1 (Ser90, Ser93, Ser96) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human BECN1 (Accession Q14457), corresponding to amino acid residues around phosphorylated Ser90 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817075 |
Product Specific Information
This antibody detects endogenous levels of Beclin 1 only when phosphorylated at Ser90/93/96.
Target Information
Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms are involved in multiple membrane trafficking pathways:
- PI3KC3-C1: Initiation of autophagosomes
- PI3KC3-C2: Maturation of autophagosomes and endocytosis
Beclin 1 also contributes to antiviral host defense mechanisms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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