Thermo Fisher Scientific Phospho-MEF2D (Ser180) Polyclonal Antibody
MEF2D 단백질의 Ser180 인산화 형태를 특이적으로 인식하는 rabbit polyclonal antibody. Western blot과 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MEF2D (Accession Q14814), corresponding to amino acid residues around phosphorylated Ser180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817077 |
Product Specific Information
This antibody detects endogenous levels of MEF2D only when phosphorylated at Ser180.
Target Information
The MEF2D gene belongs to the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family regulate muscle and neuronal cell differentiation and development, and are influenced by class II histone deacetylases. Fusions with DAZAP1 due to translocation have been identified in acute lymphoblastic leukemia cell lines, suggesting a role in leukemogenesis. The protein may also be involved in Parkinson’s disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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