Thermo Fisher Scientific C1r Polyclonal Antibody
Human C1r 단백질을 인식하는 Goat Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 인체 C1 보체 복합체 연구에 유용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Complement Component C1r (Ser18–Asp705) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609841 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human Complement Component C1s is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
C1 component of human complement is a complex of three glycoproteins: C1q, C1r, and C1s.
C1r has a molecular weight of approximately 83,000 and is present in plasma at an average concentration of 50 µg/mL, either as a complex with C1q and C1s or as a tetramer with C1s in the absence of C1q.
These subcomponents of the C1 complex are responsible for initiating the classical pathway of complement activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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