
Thermo Fisher Scientific TREM2 Polyclonal Antibody
Thermo Fisher Scientific의 TREM2 폴리클로날 항체는 Mouse TREM2 단백질을 인식하며, WB, ICC/IF, ELISA에 적합합니다. 항원 친화 크로마토그래피로 정제된 Lyophilized 형태로 제공되며, 높은 특이성과 낮은 교차반응을 보입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–15 µg/mL |
| ELISA | Assay-Dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse TREM-2b (Leu19–Pro168) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2605803 |
Product Specific Information
- In direct ELISAs, approximately 30% cross-reactivity with recombinant human TREM-2 is observed.
- Less than 1% cross-reactivity with recombinant mouse TREM-1 and TREM-3 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
TREM2 is a membrane protein forming a receptor signaling complex with TYROBP. It may play a role in chronic inflammation by triggering the production of constitutive inflammatory cytokines.
Defects in this gene are associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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