Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI1A7), TrueMAB
HBS1L 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1A7). Western blot에 최적화되어 있으며, Human 시료에 반응. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용으로 적합한 고순도 항체.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–260 of human HBS1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to reach a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The HBS1L gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with the highest expression in heart and skeletal muscle.
The intergenic region between HBS1L and MYB genes is a quantitative trait locus (QTL) controlling fetal hemoglobin levels and influencing erythrocyte, platelet, and monocyte counts, as well as erythrocyte volume and hemoglobin content.
DNA polymorphisms in this region are associated with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 correlates with severity in beta-thalassemia/Hemoglobin E.
Multiple alternatively spliced transcript variants encoding different protein isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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